Klinik für Psychiatrie und Psychotherapie, Von-Siebold-Straße 5, 37075 Göttingen
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Demiroglu SY, Skrowny D, Quade M, Schwanke J, Budde M, Gullatz V, Reich-Erkelenz D, Jakob JJ, Falkai P, Rienhoff O, Helbing K, Heilbronner U, Schulze TG (2012).
Managing sensitive phenotypic data and biomaterial in large-scale collaborative psychiatric genetic research projects: practical considerations.
Mol Psychiatry. 2012 Mar 6. doi: 10.1038/mp.2012.11. [Epub ahead of print]
Gamazon ER, Badner JA, Cheng L, Zhang C, Zhang D, Cox NJ, Gershon ES, Kelsoe JR, Greenwood TA, Nievergelt CM, Chen C, McKinney R,
Shilling PD, Schork NJ, Smith EN, Bloss CS, Nurnberger JI, Edenberg HJ, Foroud T, Koller DL, Scheftner WA, Coryell W, Rice J, Lawson WB,
Nwulia EA, Hipolito M, Byerley W, McMahon FJ, Schulze TG, Berrettini WH, Potash JB, Zandi PP, Mahon PB, McInnis MG, Zöllner S,
Zhang P, Craig DW, Szelinger S, Barrett TB, Liu C (2012).
Enrichment of cis-regulatory gene expression SNPs and methylation quantitative trait loci among bipolar disorder susceptibility variants.
Mol Psychiatry. 2012 Jan 3. doi: 10.1038/mp.2011.174. [Epub ahead of print]
Schmahl C, Ludäscher P, Greffrath W, Kraus A, Valerius G, Schulze TG, Treutlein J, Rietschel M, Smolka MN, Bohus M (2012).
COMT val158met Polymorphism and Neural Pain Processing.
PLoS One 7(1): e23658
2011 |
Belmonte Mahon P, Pirooznia M, Goes FS, Seifuddin F, Steele J, Lee PH, Huang J, Hamshere ML; The Bipolar Genome Study (BiGS)
Consortium, The Wellcome Trust Case Control Consortium Bipolar Disorder Group, Depaulo JR Jr, Kelsoe JR, Rietschel M, Nöthen M,
Cichon S, Gurling H, Purcell S, Smoller JW, Craddock N, Schulze TG, McMahon FJ, Potash JB, Zandi PP (2011).
Genome-wide association analysis of age at onset and psychotic symptoms in bipolar disorder.
AAm J Med Genet B Neuropsychiatr Genet 156(3): 370-378
Cichon S, Mühleisen TW, Degenhardt FA, Mattheisen M, Miró X, Strohmaier J, Steffens M, Meesters C, Herms S, Weingarten M, Priebe L,
Haenisch B, Alexander M, Vollmer J, Breuer R, Schmäl C, Tessmann P, Moebus S, Wichmann HE, Schreiber S, Müller-Myhsok B, Lucae S, Jamain S,
Leboyer M, Bellivier F, Etain B, Henry C, Kahn JP, Heath S; Bipolar Disorder Genome Study (BiGS) Consortium, Hamshere M, O'Donovan MC,
Owen MJ, Craddock N, Schwarz M, Vedder H, Kammerer-Ciernioch J, Reif A, Sasse J, Bauer M, Hautzinger M, Wright A, Mitchell PB, Schofield PR,
Montgomery GW, Medland SE, Gordon SD, Martin NG, Gustafsson O, Andreassen O, Djurovic S, Sigurdsson E, Steinberg S, Stefansson H, Stefansson K,
Kapur-Pojskic L, Oruc L, Rivas F, Mayoral F, Chuchalin A, Babadjanova G, Tiganov AS, Pantelejeva G, Abramova LI, Grigoroiu-Serbanescu M,
Diaconu CC, Czerski PM, Hauser J, Zimmer A, Lathrop M, Schulze TG, Wienker TF, Schumacher J, Maier W, Propping P, Rietschel M, Nöthen MM (2011).
Genome-wide Association Study Identifies Genetic Variation in Neurocan as a Susceptibility Factor for Bipolar Disorder.
Am J Hum Genet 88(3): 372-81
Falkai P, Gruber O, Schulze TG, Schmitt A (2011).
Schizophrenie als Netzwerkstörung. Von einer Dysfunktion neuronaler Verbünde zu einer Dysregulation von Gennetzen.
Nervenheilkunde 30: 218-223
Goes FS, Rongione M, Chen YC, Karchin R, Elhaik E; Bipolar Genome Study, Potash JB (2011).
Exonic DNA sequencing of ERBB4 in bipolar disorder.
PLoS One 6(5): e20242
Gupta A, Schulze TG, Nagarajan V, Akula N, Corona W, Jiang XY, Hunter N, McMahon FJ, Detera-Wadleigh SD (2011).
Interaction networks of lithium and valproate molecular targets reveal a striking enrichment of apoptosis functional clusters and neurotrophin signaling.
Pharmacogenomics J. 2011 Mar 8. [Epub ahead of print]
Håvik B, Le Hellard S, Rietschel M, Lybæk H, Djurovic S, Mattheisen M, Mühleisen TW, Degenhardt F, Priebe L, Maier W, Breuer R,
Schulze TG, Agartz I, Melle I, Hansen T, Bramham CR, Nöthen MM, Stevens B, Werge T, Andreassen OA, Cichon S, Steen VM (2011).
The Complement Control-Related Genes CSMD1 and CSMD2 Associate to Schizophrenia.
Biol Psychiatry 70(1): 35-42
Leon CA, Schumacher J, Kluck N, Herold C, Schulze TG, Propping P, Rietschel M, Cichon S, Nöthen MM, Jamra RA (2011).
Association study of the GRIA1 and CLINT1 (Epsin 4) genes in a German schizophrenia sample.
Psychiatr Genet 21(2): 114
Malhotra D, McCarthy S, Michaelson JJ, Vacic V, Burdick KE, Yoon S, Cichon S, Corvin A, Gary S, Gershon ES, Gill M, Karayiorgou M,
Kelsoe JR, Krastoshevsky O, Krause V, Leibenluft E, Levy DL, Makarov V, Bhandari A, Malhotra AK, McMahon FJ, Nöthen MM, Potash JB,
Rietschel M, Schulze TG, Sebat J (2011).
High Frequencies of De Novo CNVs in Bipolar Disorder and Schizophrenia.
Neuron 72(6): 951-63
Rietschel M, Mattheisen M, Degenhardt F; GROUP Investigators; Genetic Risk and Outcome in Psychosis (GROUP Investigators),
Kahn RS, Linszen DH, Os JV, Wiersma D, Bruggeman R, Cahn W, de Haan L, Krabbendam L, Myin-Germeys I, Mühleisen TW, Kirsch P,
Esslinger C, Herms S, Demontis D, Steffens M, Strohmaier J, Haenisch B, Breuer R, Czerski PM, Giegling I, Strengman E, Schmael C,
Mors O, Mortensen PB, Hougaard DM, Orntoft T, Kapelski P, Priebe L, Basmanav FB, Forstner AJ, Hoffmann P, Meier S, Nikitopoulos J,
Moebus S, Alexander M, Mössner R, Wichmann HE, Schreiber S, Rivandeneira F, Hofman A, Uitterlinden AG, Wienker TF, Schumacher J,
Hauser J, Maier W, Cantor RM, Erk S, Schulze TG;
SGENE-plus Consortium; (Only those persons responsible for the samples of Replication 2 are listed),
Stefansson H, Steinberg S, Gustafsson O, Sigurdsson E, Petursson H, Kong A, Stefansson K, Pietiläinen OP,
Tuulio-Henriksson A, Paunio T, Lonnqvist J, Suvisaari J, Peltonen L, Ruggeri M, Tosato S, Walshe M, Murray R,
Collier DA, Clair DS, Hansen T, Ingason A, Jakobsen KD, Duong L, Werge T, Melle I, Andreassen OA, Djurovic S, Bitter I,
Réthelyi JM, Abramova L, Kaleda V, Golimbet V, Jönsson EG, Terenius L, Agartz I, Winkel RV, Kenis G, Hert MD, Veldink J,
Wiuf C, Didriksen M, Craddock N, Owen MJ, O'Donovan MC, Børglum AD, Rujescu D, Walter H, Meyer-Lindenberg A, Nöthen MM,
Ophoff RA, Cichon S (2011).
Association between genetic variation in a region on chromosome 11 and schizophrenia in large samples from Europe.
Mol Psychiatry. 2011 Jul 12. doi: 10.1038/mp.2011.80. [Epub ahead of print]
Ripke S, Sanders AR, Kendler KS, Levinson DF, Sklar P, Holmans PA, Lin DY, Duan J, Ophoff RA, Andreassen OA, Scolnick E, Cichon S,
St Clair D, Corvin A, Gurling H, Werge T, Rujescu D, Blackwood DH, Pato CN, Malhotra AK, Purcell S, Dudbridge F, Neale BM, Rossin L,
Visscher PM, Posthuma D, Ruderfer DM, Fanous A, Stefansson H, Steinberg S, Mowry BJ, Golimbet V, De Hert M, Jönsson EG, Bitter I,
Pietiläinen OP, Collier DA, Tosato S, Agartz I, Albus M, Alexander M, Amdur RL, Amin F, Bass N, Bergen SE, Black DW, Børglum AD,
Brown MA, Bruggeman R, Buccola NG, Byerley WF, Cahn W, Cantor RM, Carr VJ, Catts SV, Choudhury K, Cloninger CR, Cormican P, Craddock N,
Danoy PA, Datta S, de Haan L, Demontis D, Dikeos D, Djurovic S, Donnelly P, Donohoe G, Duong L, Dwyer S, Fink-Jensen A, Freedman R,
Freimer NB, Friedl M, Georgieva L, Giegling I, Gill M, Glenthøj B, Godard S, Hamshere M, Hansen M, Hansen T, Hartmann AM, Henskens FA,
Hougaard DM, Hultman CM, Ingason A, Jablensky AV, Jakobsen KD, Jay M, Jürgens G, Kahn RS, Keller MC, Kenis G, Kenny E, Kim Y, Kirov GK,
Konnerth H, Konte B, Krabbendam L, Krasucki R, Lasseter VK, Laurent C, Lawrence J, Lencz T, Lerer FB, Liang KY, Lichtenstein P,
Lieberman JA, Linszen DH, Lönnqvist J, Loughland CM, Maclean AW, Maher BS, Maier W, Mallet J, Malloy P, Mattheisen M, Mattingsdal M,
McGhee KA, McGrath JJ, McIntosh A, McLean DE, McQuillin A, Melle I, Michie PT, Milanova V, Morris DW, Mors O, Mortensen PB, Moskvina V,
Muglia P, Myin-Germeys I, Nertney DA, Nestadt G, Nielsen J, Nikolov I, Nordentoft M, Norton N, Nöthen MM, O'Dushlaine CT, Olincy A,
Olsen L, O'Neill FA, Orntoft TF, Owen MJ, Pantelis C, Papadimitriou G, Pato MT, Peltonen L, Petursson H, Pickard B, Pimm J, Pulver AE,
Puri V, Quested D, Quinn EM, Rasmussen HB, Réthelyi JM, Ribble R, Rietschel M, Riley BP, Ruggeri M, Schall U, Schulze TG, Schwab SG,
Scott RJ, Shi J, Sigurdsson E, Silverman JM, Spencer CC, Stefansson K, Strange A, Strengman E, Stroup TS, Suvisaari J, Terenius L,
Thirumalai S, Thygesen JH, Timm S, Toncheva D, van den Oord E, van Os J, van Winkel R, Veldink J, Walsh D, Wang AG, Wiersma D,
Wildenauer DB, Williams HJ, Williams NM, Wormley B, Zammit S, Sullivan PF, O'Donovan MC, Daly MJ, Gejman PV;
Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium (2011).
Genome-wide association study identifies five new schizophrenia loci.
Nat Genet 43(10): 969-76
Sklar P, Ripke S, Scott LJ, Andreassen OA, Cichon S, Craddock N, Edenberg HJ, Nurnberger JI Jr, Rietschel M, Blackwood D, Corvin A,
Flickinger M, Guan W, Mattingsdal M, McQuillin A, Kwan P, Wienker TF, Daly M, Dudbridge F, Holmans PA, Lin D, Burmeister M,
Greenwood TA, Hamshere ML, Muglia P, Smith EN, Zandi PP, Nievergelt CM, McKinney R, Shilling PD, Schork NJ, Bloss CS, Foroud T,
Koller DL, Gershon ES, Liu C, Badner JA, Scheftner WA, Lawson WB, Nwulia EA, Hipolito M, Coryell W, Rice J, Byerley W, McMahon FJ,
Schulze TG, Berrettini W, Lohoff FW, Potash JB, Mahon PB, McInnis MG, Zöllner S, Zhang P, Craig DW, Szelinger S, Barrett TB,
Breuer R, Meier S, Strohmaier J, Witt SH, Tozzi F, Farmer A, McGuffin P, Strauss J, Xu W, Kennedy JL, Vincent JB, Matthews K, Day R,
Ferreira MA, O'Dushlaine C, Perlis R, Raychaudhuri S, Ruderfer D, Hyoun PL, Smoller JW, Li J, Absher D, Thompson RC, Meng FG,
Schatzberg AF, Bunney WE, Barchas JD, Jones EG, Watson SJ, Myers RM, Akil H, Boehnke M, Chambert K, Moran J, Scolnick E, Djurovic S,
Melle I, Morken G, Gill M, Morris D, Quinn E, Mühleisen TW, Degenhardt FA, Mattheisen M, Schumacher J, Maier W, Steffens M, Propping P,
Nöthen MM, Anjorin A, Bass N, Gurling H, Kandaswamy R, Lawrence J, McGhee K, McIntosh A, McLean AW, Muir WJ, Pickard BS, Breen G,
St Clair D, Caesar S, Gordon-Smith K, Jones L, Fraser C, Green EK, Grozeva D, Jones IR, Kirov G, Moskvina V, Nikolov I, O'Donovan MC,
Owen MJ, Collier DA, Elkin A, Williamson R, Young AH, Ferrier IN, Stefansson K, Stefansson H, Thornorgeirsson T, Steinberg S,
Gustafsson O, Bergen SE, Nimgaonkar V, Hultman C, Landén M, Lichtenstein P, Sullivan P, Schalling M, Osby U, Backlund L, Frisén L,
Langstrom N, Jamain S, Leboyer M, Etain B, Bellivier F, Petursson H, Sigur Sson E, Müller-Mysok B, Lucae S, Schwarz M, Schofield PR,
Martin N, Montgomery GW, Lathrop M, Oskarsson H, Bauer M, Wright A, Mitchell PB, Hautzinger M, Reif A, Kelsoe JR, Purcell SM;
Psychiatric GWAS Consortium Bipolar Disorder Working Group (2011).
Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4.
Nat Genet 43(10): 977-83
Smith EN, Koller DL, Panganiban C, Szelinger S, Zhang P, Badner JA, Barrett TB, Berrettini WH, Bloss CS, Byerley W, Coryell W,
Edenberg HJ, Foroud T, Gershon ES, Greenwood TA, Guo Y, Hipolito M, Keating BJ, Lawson WB, Liu C, Mahon PB, McInnis MG, McMahon FJ,
McKinney R, Murray SS, Nievergelt CM, Nurnberger JI Jr, Nwulia EA, Potash JB, Rice J, Schulze TG, Scheftner WA, Shilling PD, Zandi PP,
Zöllner S, Craig DW, Schork NJ, Kelsoe JR (2011).
Genome-wide association of bipolar disorder suggests an enrichment of replicable associations in regions near genes.
PLoS Genet 7(6): e1002134
Willour VL, Seifuddin F, Mahon PB, Jancic D, Pirooznia M, Steele J, Schweizer B, Goes FS, Mondimore FM, Mackinnon DF;
The Bipolar Genome Study (BiGS) Consortium, Perlis RH, Lee PH, Huang J, Kelsoe JR, Shilling PD, Rietschel M, Nöthen M, Cichon S,
Gurling H, Purcell S, Smoller JW, Craddock N, Depaulo JR Jr, Schulze TG, McMahon FJ, Zandi PP, Potash JB (2011).
A genome-wide association study of attempted suicide.
Mol Psychiatry. 2011 Mar 22. [Epub ahead of print]
Zhang D, Qian Y, Akula N, Alliey-Rodriguez N, Tang J; Bipolar Genome Study, Gershon ES, Liu C (2011).
Accuracy of CNV Detection from GWAS Data.
PLoS One 6(1): e14511
2010 |
Abboud Leon C, Schumacher J, Kluck N, Herold C, Schulze TG, Propping P, Rietschel M, Cichon S, Nöthen MM, Abou Jamra R (2010).
Association study of the GRIA1 and CLINT1 (Epsin 4) genes in a German schizophrenia sample.
Psychiatr Genet. 2010 Nov 24. [Epub ahead of print]
Abou Jamra R, Schulze TG, Becker T, Brockschmidt FF, Green E, Alblas MA, Wendland JR, Adli M, Grozeva D, Strohmeier J, Georgi A, Craddock N,
Propping P, Rietschel M, Nöthen MM, Cichon S, Schumacher J (2010).
A systematic association mapping on chromosome 6q in bipolar affective disorder--evidence for the melanin-concentrating-hormone-receptor-2 gene
as a risk factor for bipolar affective disorder.
Am J Med Genet B Neuropsychiatr Genet 153B(4): 878-84
Breuer R, Hamshere ML, Strohmaier J, Mattheisen M, Degenhardt F, Meier S, Paul T, O'Donovan MC, Mühleisen TW, Schulze TG,
Nöthen MM, Cichon S, Craddock N, Rietschel M (2010).
Independent evidence for the selective influence of GABA(A) receptors on one component of the bipolar disorder phenotype.
Mol Psychiatry. 2010 Jun 15. [Epub ahead of print]
Deuschle M, Schredl M, Schilling C, Wüst S, Frank J, Witt SH, Rietschel M, Buckert M, Meyer-Lindenberg A, Schulze TG (2010).
Association between a serotonin transporter length polymorphism and primary insomnia.
Sleep 33(3): 343-7
Keers R, Uher R, Gupta B, Rietschel M, Schulze TG, Hauser J, Skibinska M, Henigsberg N, Kalember P, Maier W, Zobel A, Mors O,
Kristensen AS, Kozel D, Giovannini C, Mendlewicz J, Kumar S, McGuffin P, Farmer AE, Aitchison KJ (2010).
Stressful life events, cognitive symptoms of depression and response to antidepressants in GENDEP.
J Affect Disord. 2010 Jul 5. [Epub ahead of print]
Mathieu F, Dizier MH, Etain B, Jamain S, Rietschel M, Maier W, Albus M, McKeon P, Roche S, Blackwood D, Muir WJ, Henry C, Malafosse A, Preisig M,
Ferrero F, Cichon S, Schumacher J, Ohlraun S, Propping P, Abou Jamra R, Schulze TG, Zelenica D, Charon C, Marusic A, Dernovsek MC, Gurling H,
Nöthen M, Lathrop M, Leboyer M, Bellivier F (2010).
European collaborative study of early-onset bipolar disorder: Evidence for genetic heterogeneity on 2q14 according to age at onset.
Am J Med Genet B Neuropsychiatr Genet 153B(8): 1425-33
McMahon FJ, Akula N, Schulze TG, Muglia P, Tozzi F, Detera-Wadleigh SD, Steele CJ, Breuer R, Strohmaier J, Wendland JR, Mattheisen M,
Mühleisen TW, Maier W, Nöthen MM, Cichon S, Farmer A, Vincent JB, Holsboer F, Preisig M, Rietschel M.,
the Bipolar Disorder Genome Study (BiGS) Consortium (2010).
Meta-analysis of genome-wide association data identifies a risk locus for major mood disorders on 3p21.1.
Nat Genet. 2010 Jan 17. [Epub ahead of print]
Nieratschker V, Frank J, Mühleisen TW, Strohmaier J, Wendland JR, Schumacher J, Treutlein J, Breuer R, Jamra RA, Mattheisen M,
Herms S, Schmäl C, Maier W, Nöthen MM, Cichon S, Rietschel M, Schulze TG (2010).
The catechol-O-methyl transferase (COMT) gene and its potential association with schizophrenia:
Findings from a large German case-control and family-based sample.
Schizophr Res. 2010 Jul 19. [Epub ahead of print]
Perlis RH, Huang J, Purcell S, Fava M, Rush AJ, Sullivan PF, Hamilton SP, McMahon FJ, Schulze TG, Potash JB, Zandi PP, Willour VL, Penninx BW,
Boomsma DI, Vogelzangs N, Middeldorp CM, Rietschel M, Nöthen M, Cichon S, Gurling H, Bass N, McQuillin A, Hamshere M;
Wellcome Trust Case Control Consortium Bipolar Disorder Group, Craddock N, Sklar P, Smoller JW (2010).
Genome-wide association study of suicide attempts in mood disorder patients.
Am J Psychiatry 167(12): 1499-507; Erratum in: Am J Psychiatry. 2011 168(1): 100
Rietschel M, Mattheisen M, Frank J, Treutlein J, Degenhardt F, Breuer R, Steffens M, Mier D, Esslinger C, Walter H, Kirsch P, Erk S,
Schnell K, Herms S, Wichmann HE, Schreiber S, Jöckel KH, Strohmaier J, Roeske D, Haenisch B, Gross M, Hoefels S, Lucae S, Binder EB,
Wienker TF, Schulze TG, Schmäl C, Zimmer A, Juraeva D, Brors B, Bettecken T, Meyer-Lindenberg A, Müller-Myhsok B, Maier W, Nöthen MM, Cichon S (2010).
Genome-Wide Association-, Replication-, and Neuroimaging Study Implicates HOMER1 in the Etiology of Major Depression.
Biol Psychiatry 68(6): 578-85
Schulze TG.
Genetic research into bipolar disorder: the need for a research framework that integrates sophisticated molecular biology and
clinically-informed phenotype characterization.
Psych Clin North America, in press
Schulze TG, Alda M, Adli M, Akula N, Ardau R, Bui ET, Chillotti C, Cichon S, Czerski P, Del Zompo M, Detera-Wadleigh SD, Grof P, Gruber O,
Hashimoto R, Hauser J, Hoban R, Iwata N, Kassem L, Kato T, Kittel-Schneider S, Kliwicki S, Kelsoe JR, Kusumi I, Laje G, Leckband SG, Manchia M,
Macqueen G, Masui T, Ozaki N, Perlis RH, Pfennig A, Piccardi P, Richardson S, Rouleau G, Reif A, Rybakowski JK, Sasse J, Schumacher J, Severino G,
Smoller JW, Squassina A, Turecki G, Young LT, Yoshikawa T, Bauer M, McMahon FJ (2010).
The International Consortium on Lithium Genetics (ConLiGen): an initiative by the NIMH and IGSLI to study the genetic basis of response to lithium treatment.
Neuropsychobiology 62(1): 72-8
Strohmaier J, Frank J, Wendland JR, Schumacher J, Jamra RA, Treutlein J, Nieratschker V, Breuer R, Mattheisen M, Herms S, Mühleisen TW,
Maier W, Nöthen MM, Cichon S, Rietschel M, Schulze TG (2010).
A reappraisal of the association between Dysbindin (DTNBP1) and schizophrenia in a large combined case-control and family-based sample of German ancestry.
Schizophr Res. 2010 Jan 16. [Epub aheadof print]
Suliman H, Schumacher J, Becker T, Cichon S, Schulze TG, Propping P, Rietschel M, Nöthen MM, Jamra RA (2010).
Association study of 20 genetic variants at the (D)-amino acid oxidase gene in schizophrenia.
Psychiatr Genet 20(2): 82-3
Uher R, Perroud N, Ng MY, Hauser J, Henigsberg N, Maier W, Mors O, Placentino A, Rietschel M, Souery D, Zagar T, Czerski PM,
Jerman B, Larsen ER, Schulze TG, Zobel A, Cohen-Woods S, Pirlo K, Butler AW, Muglia P, Barnes MR, Lathrop M, Farmer A, Breen G, Aitchison KJ, Craig I,
Lewis CM, McGuffin P (2010).
Genome-wide pharmacogenetics of antidepressant response in the GENDEP project.
Am J Psychiatry 167(5): 555-64
2009 |
Abou Jamra R, Schulze TG, Becker T, Brockschmidt FF, Green E, Alblas MA, Wendland JR, Adli M, Grozeva D, Strohmaier J, Georgi A, Craddock N,
Propping P, Rietschel M, Nöthen MM, Cichon S, Schumacher J (2009).
A systematic association mapping on chromosome 6q in bipolar affective disorder-evidence for the melanin-concentrating-hormone-receptor-2
gene as a risk factor for bipolar affective disorder.
Am J Med Genet B Neuropsychiatr Genet. 2009 Nov 19. [Epub ahead of print]
Cross Disorder Phenotype Group of the Psychiatric GWAS Consortium (2009).
Dissecting the phenotype in genome-wide association studies of psychiatric illness.
Brit J Psychiatry 195: 97-99
Georgi A, Schumacher J, Leon CA, Wolf AV, Klein K, Böhenz KV, Schirmbeck F, Strohmaier J, Propping P, Schulze TG, Rietschel M,
Nöthen MM, Cichon S, Jamra RA (2009).
No association between genetic variants at the DGCR2 gene and schizophrenia in a German sample.
Psychiatr Genet 19: 104
Goes FS, Willour VL, Zandi PP, Belmonte PL, Mackinnon DF, Mondimore FM, Schweizer B, Gershon ES, McMahon FJ, Potash JB; Bipolar Disorder Phenome Group,
NIMH Genetics Initiative Bipolar Disorder Consortium (2009).
Family-based association study of Neuregulin 1 with psychotic bipolar disorder.
Am J Med Genet B Neuropsychiatr Genet 150B: 693-702
Grover D, Verma R, Goes FS, Mahon PL, Gershon ES, McMahon FJ, Potash JB; NIMH Genetics Initiative Bipolar Disorder
Collaborative, Bipolar Disorder Phenome Group (2009).
Family-based association of YWHAH in psychotic bipolar disorder.
Am J Med Genet B Neuropsychiatr Genet. 2009 Jan 21. [Epub ahead of print]
Hamshere ML, Schulze TG, Schumacher J, Corvin A, Owen MJ, Jamra RA, Propping P, Maier W, Orozco y Diaz G, Mayoral F, Rivas F, Jones I, Jones L,
Kirov G, Gill M, Holmans PA, Nöthen MM, Cichon S, Rietschel M, Craddock N (2009).
Mood-incongruent psychosis in bipolar disorder: conditional linkage analysis shows genome-wide suggestive linkage at 1q32.3, 7p13 and 20q13.31.
Bipolar Disord 11: 610-620
Jamra RA, Georgi A, Suliman H, Klein K, Villela AW, Schulze TG, Propping P, Cichon S, Rietschel M, Nöthen MM, Schumacher J (2009).
No association between the D-aspartate oxidase locus and schizophrenia.
Psychiatr Genet 19: 56
Mahon PB, Payne JL, MacKinnon DF, Mondimore FM, Goes FS, Schweizer B, Jancic D; NIMH Genetics Initiative Bipolar Disorder
Consortium; BiGS Consortium, Coryell WH, Holmans PA, Shi J, Knowles JA, Scheftner WA, Weissman MM, Levinson DF, DePaulo JR Jr, Zandi PP, Potash JB (2009).
Genome-wide linkage and follow-up association study of postpartum mood symptoms.
Am J Psychiatry 2009; 166:1229-1237
McCarthy SE, Makarov V, Kirov G, Addington AM, McClellan J, Yoon S, Perkins DO, Dickel DE, Kusenda M, Krastoshevsky O, Krause V, Kumar RA, Grozeva D,
Malhotra D, Walsh T, Zackai EH, Kaplan P, Ganesh J, Krantz ID, Spinner NB, Roccanova P, Bhandari A, Pavon K, Lakshmi B, Leotta A, Kendall J, Lee YH,
Vacic V, Gary S, Iakoucheva LM, Crow TJ, Christian SL, Lieberman JA, Stroup TS, Lehtimäki T, Puura K, Haldeman-Englert C, Pearl J, Goodell M, Willour VL,
Derosse P, Steele J, Kassem L, Wolff J, Chitkara N, McMahon FJ, Malhotra AK, Potash JB, Schulze TG, Nöthen MM, Cichon S, Rietschel M, Leibenluft E,
Kustanovich V, Lajonchere CM, Sutcliffe JS, Skuse D, Gill M, Gallagher L, Mendell NR; Wellcome Trust Case Control Consortium, Craddock N, Owen MJ,
O'Donovan MC, Shaikh TH, Susser E, Delisi LE, Sullivan PF, Deutsch CK, Rapoport J, Levy DL, King MC, Sebat J (2009).
Microduplications of 16p11.2 are associated with schizophrenia.
Nat Genet 41: 1223-1227
O Donovan MC, Norton N, Williams H, Peirce T, Moskvina V, Nikolov I, Hamshere M, Carroll L, Georgieva L, Dwyer S, Holmans P, Marchini JL,
Spencer CCA, Howie B, Leung H-T, Giegling I, Hartmann AM, Möller H-J, Morris DW, Shi Y, Feng G, Hoffmann P, Propping P, Vasilescu C, Maier W,
Rietschel M, Zammit S, Schumacher J, Quinn EM, Schulze TG, Iwata N, Ikeda M, Darvasi A, Shifman S, He L, Duan J, Sanders AR, Levinson DF,
Adolfsson R, Ösby U, Terenius L, Jönsson EC, Molecular Genetics of Schizophrenia Collaboration, Cichon S, Nöthen MM, Gill M, Corvin AP,
Rujescu D, Gejman PV, Kirov G, Craddock N, Williams NM, Owen MJ (2009).
Analysis of 10 independent samples provides evidence for association between schizophrenia and a SNP flanking fibroblast growth factor receptor 2 (FGFR2).
Mol Psychiatry 14: 30-36
Perroud N, Aitchison KJ, Uher R, Smith R, Huezo-Diaz P, Marusic A, Maier W, Mors O, Placentino A, Henigsberg N, Rietschel M, Hauser J, Souery D,
Kapelski P, Bonvicini C, Zobel A, Jorgensen L, Petrovic A, Kalember P, Schulze TG, Gupta B, Gray J, Lewis CM, Farmer AE, McGuffin P, Craig I (2009).
Predictors of increase in suicidal ideation during antidepressant treatment in the GENDEP project.
Neuropsychopharmacology 34: 2517-2528
Rietschel M, Georgi A, Schmäl C, Schirmbeck F, Strohmaier J, Boesshenz KV, Schwarz M, Nöthen MM, Schulze TG (2009).
Premorbid Adjustment: a phenotype highlighting distinction rather than overlap between schizophrenia and bipolar disorder.
Schizophrenia Res 110: 33-39
Schulze TG, Detera-Wadleigh SD, Akula N, Gupta A, Kassem L, Steele J, Pearl J, Strohmaier J, Breuer R, Schwarz M, Propping P,
Nöthen MM, Cichon S, Schumacher J;NIMH Genetics Initiative Bipolar Disorder Consortium7, Rietschel M, McMahon FJ (2009).
Two variants in Ankyrin 3 (ANK3) are independent genetic risk factors for bipolar disorder.
Mol Psychiatry 14: 487-491
Schumacher J, Laje G, Abou Jamra R, Becker T, Mühleisen TW, Vasilescu C, Mattheisen M, Herms S, Hoffmann P, Hillmer AM, Georgi A, Herold C,
Schulze TG, Propping P, Rietschel M, McMahon FJ, Nöthen MM, Cichon S (2009).
The DISC locus and schizophrenia - Evidence from an association study in a central European sample and from a meta-analysis across different European populations.
Hum Mol Genet 18: 2719-2727
Schulze TG, McMahon FJ.
The Genetics of Bipolar Disorder. In: Molecular Neurobiology, Clinical Diagnosis, and Pharmacotherapy (Zarate CA and Manji HK, eds).
Basel 2009, Birkhäuser Publishing
Smith EN, Bloss CS, Badner JA, Barrett T, Belmonte PL, Berrettini W, Byerley W, Coryell W, Craig D, Edenberg HJ, Eskin E, Foroud T, Gershon E,
Greenwood TA, Hipolito M, Koller DL, Lawson WB, Liu C, Lohoff F, McInnis MG, McMahon FJ, Mirel DB, Murray SS, Nievergelt C, Nurnberger J, Nwulia EA,
Paschall J, Potash JB, Rice J, Schulze TG, Scheftner W, Panganiban C, Zaitlen N, Zandi PP, Zöllner S, Schork NJ, Kelsoe JR (2009).
Genome-wide association study of bipolar disorder in European American and African American individuals.
Mol Psychiatry 14: 755-763
Tost H, Ruf M, Schmäl C, Schulze TG, Knorr C, Vollmert C, Bößhenz K, Ende G, Meyer-Lindenberg A, Henn FA, Rietschel M (2009).
Prefrontal-temporal gray matter deficits in bipolar disorder patients with persecutory delusions.
J Affect Disord. 2009 May 4. [Epub ahead of print]
Treutlein J, Mühleisen TW, Frank J, Mattheisen M, Herms S, Treutlein T, Schmäl C, Strohmaier J, Boesshenz KV, Breuer R, Paul T,
Witt SH, Schulze TG, Schlösser RG, Nenadic I, Sauer H, Becker T, Maier W, Cichon S, Nöthen MM, Rietschel M (2009).
Dissection of phenotype reveals possible association between schizophrenia and Glutamate Receptor Delta 1 (GRID1) gene promoter.
Schizophr Res 111: 123-130
Uher R, Huezo-Diaz P, Perroud N, Smith R, Rietschel M, Mors O, Hauser J, Maier W, Kozel D, Henigsberg N, Barreto M, Placentino A,
Dernovsek MZ, Schulze TG, Kalember P, Zobel A, Czerski PM, Larsen ER, Souery D, Giovannini C, Gray JM, Lewis CM, Farmer A, Aitchison KJ,
McGuffin P, Craig I (2009).
Genetic predictors of response to antidepressants in the GENDEP project.
Pharmacogenomics J 9: 225-233
Willour VL, Chen H, Toolan J, Belmonte P, Cutler DJ, Goes FS, Zandi PP, Lee RS, MacKinnon DF, Mondimore FM, Schweizer B;
Bipolar Disorder Phenome Group; NIMH Genetics Initiative Bipolar Disorder Consortium, DePaulo JR Jr, Gershon ES, McMahon FJ, Potash JB.
Family-based association of FKBP5 in bipolar disorder.
Mol Psychiatry 14: 261-268
Wüst S, Kumsta R, Treutlein J, Frank J, Entringer S, Schulze TG, Rietschel M (2009).
Sex-specific association between the 5-HTT gene-linked polymorphic region and basal cortisol secretion.
Psychoneuroendocrinology 34: 972-982
Zhang D, Cheng L, Qian Y, Alliey-Rodriguez N, Kelsoe JR, Greenwood T,Nievergelt C, Barrett TB, McKinney R, Schork N, Smith EN, Bloss C,
Nurnberger J, Edenberg HJ, Foroud T, Sheftner W, Lawson WB, Nwulia EA, Hipolito M, Coryell W, Rice J, Byerley W, McMahon F, Schulze TG,
Berrettini W, Potash JB, Belmonte PL, Zandi PP, McInnis MG, Zöllner S, Craig D, Szelinger S, Koller D, Christian SL, Liu C, Gershon ES (2009).
Singleton deletions throughout the genome increase risk of bipolar disorder.
Mol Psychiatry 14: 376-380
2008 |
Abou Jamra R, Becker T, Georgi A, Feulner T, Schumacher J, Stromaier J, Schirmbeck F, Schulze TG, Propping P, Rietschel M, Nöthen MM, Cichon S (2008).
Genetic variation of the FAT gene at 4q35 is associated with bipolar affective disorder.
Mol Psychiatry 13: 277-284
Abou Jamra R, Gobina CM, Becker T, Georgi A, Schulze TG, Schmael C, Cichon S,Propping P, Rietschel M, Nöthen MM, Schumacher J (2008).
Association study between genetic variants at the VAMP2 and VAMP3 loci and bipolar affective disorder.
Psychiatr Genet 18: 199-203
Baum AE, Akula N, Cabanero M, Cardona I, Corona W, Klemens B, Schulze TG, Cichon S, Rietschel M, Nöthen MM, Georgi A, Schumacher J,
Schwarz M, Abou Jamra R, Höfels S, Propping P, Satagopan J, Detera-Wadleigh SD, Hardy J, McMahon FJ (2008).
A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder.
Mol Psychiatry 13: 197-207
Cichon S, Winge I, Mattheisen M, Georgi A, Karpushova A, Freudenberg J, Freudenberg-Hua Y, Babadjanova G, Van Den Bogaert A, Abramova LI,
Kapiletti S, Knappskog PM, McKinney J, Maier W, Jamra RA, Schulze TG, Schumacher J, Propping P, Rieschel M, Haavik J, Nöthen MM (2008).
Brain-specific tryptophan hydroxylase 2 (TPH2): A functional Pro206Ser substitution and variation in the 5'-region are associated with bipolar affective disorder.
Hum Mol Genet 17: 87-97
Ebner F, Tepest R, Dani I, Pfeiffer U, Schulze TG, Rietschel M, Maier W, Träber F, Block W, Schild HH, Wagner M, Steinmetz H, Gaebel W,
Honer WG, Schneider-Axmann T, Falkai P.
The hippocampus in families with schizophrenia in relation to obstetric complications.
Schizophr Res 104: 71-78
O'Donovan MC, Craddock N, Norton N, Williams H, Peirce T, Moskvina V, Nikolov I, Hamshere M, Carroll L, Georgieva L, Dwyer S, Holmans P,
Marchini JL, Spencer CC, Howie B, Leung HT, Hartmann AM, Möller HJ, Morris DW, Shi Y, Feng G, Hoffmann P, Propping P, Vasilescu C, Maier W,
Rietschel M, Zammit S, Schumacher J, Quinn EM, Schulze TG, Williams NM, Giegling I, Iwata N, Ikeda M, Darvasi A, Shifman S, He L, Duan J,
Sanders AR, Levinson DF, Gejman PV; Molecular Genetics of schizophrenia Collaboration, Gejman PV, Sanders AR, Duan J, Levinson DF, Buccola NG,
Mowry BJ, Freedman R, Amin F, Black DW, Silverman JM, Byerley WF, Cloninger CR, Cichon S, Nöthen MM, Gill M, Corvin A, Rujescu D, Kirov G, Owen MJ (2008).
Identification of loci associated with schizophrenia by genome-wide association and follow-up.
Nat Genet 40: 1053-1055
Rietschel M, Beckmann L, Strohmaier J, Georgi A, Karpushova A, Schirmbeck F, Boesshenz KV, Schmael C, Buerger C, Abou Jamra R, Schumacher J,
Hoefels S, Kumsta R, Entringer S, Krug A, Markov V, Maier W, Propping P, Wuest S, Kircher T, Noethen MM, Cichon S, Schulze TG (2008).
G72 and its association with major depression and neuroticism in large population-based groups from Germany.
Am J Psychiatry 165: 753-762
Schirmbeck F, Georgi A, Strohmaier J, Schmael C, Boesshenz KV, Mühleisen TW, Herms S, Hoffmann P, Abou Jamra R, Schumacher J, Maier W,
Propping P, Nöthen MM, Cichon S, Rietschel M, Schulze TG (2008).
No association between premorbid adjustment in adult-onset schizophrenia and genetic variation in dysbindin.
J Autism Dev Disord 38: 1977-1981
Wobrock T, Kamer T, Roy A, Vogeley K, Schneider-Axmann T, Wagner M, Maier W, Rietschel M, Schulze TG, Scherk H, Schild HH, Block W,
Träber F, Tepest R, Honer WG, Falkai P (2008).
Reduction of the Internal Capsule in Families Affected with Schizophrenia.
Biol Psychiatry 63: 65-71
Zandi PP, Belmonte PL, Willour VL, Goes FS, Badner JA, Simpson SG, Gershon ES, McMahon FJ, DePaulo JR Jr, Potash JB;
Bipolar Disorder Phenome Group; National Institute of Mental Health Genetics Initiative Bipolar Disorder Consortium (2008).
Association study of Wnt signaling pathway genes in bipolar disorder
Arch Gen Psychiatry 65: 785
2007 |
Abou Jamra R, Becker T, Klopp N, Dahdouh F, Schulze TG, Gross M, Deschner M, Schmäl C, Illig T, Rietschel M, Propping P,
Cichon P, Nöthen MM, Schumacher J (2007).
No evidence for an association between variants at the GABAA receptor ²2 locus and schizophrenia.
Psychiatr Genet 17: 43-45
Abou Jamra R, Fuerst R, Kaneva R, Orozco Diaz G, Rivas F, Mayoral F, Gay E, Sans S, Gonzalez MJ, Gil S, Cabaleiro F, Del Rio F, Perez F,
Haro J, Auburger G, Milanova V, Kostov C, Chorbov V, Stoyanova V, Nikolova-Hill A, Onchev G, Kremensky I, Jablensky A, Schulze TG, Propping P,
Rietschel M, Nothen MM, Cichon S, Wienker TF, Schumacher J (2007).
The first genomewide interaction and locus-heterogeneity linkage scan in bipolar affective disorder: strong evidence of epistatic effects between
loci on chromosomes 2q and 6q.
Am J Hum Genet 81: 974-986
Amar S, Shamir A, Ovadia O, Blanaru M, Reshef A, Kremer I, Rietschel M, Schulze TG, Maier W, Belmaker RH, Ebstein RP, Agam G, Mishmar D (2007).
Mitochondrial DNA HV lineage increases the susceptibility to schizophrenia among Israeli Arabs.
Schizophr Res 2007; 94:354-358
Brüggemann D, Sobanski E, Alm B, Schubert T, Schmalzried H, Phillipsen A, Breen G, Becker T, Georgi A, Skowronek MH,
Schulze TG, Treutlein J, Rietschel M (2007).
No association between a common haplotype of the 6- and 10-repeat alleles in intron 8 and the 3 UTR of the DAT1 gene and adult
attention deficit hyperactivity disorder.
Psychiatr Genet 17: 121
Falkai P, Honer WG, Kamer T, Dustert S, Vogeley K, Schneider-Axmann T, Dani I, Wagner M, Rietschel M, Muller DJ, Schulze TG,
Gaebel W, Cordes J, Schonell H, Schild HH, Block W, Traber F, Steinmetz H, Maier W, Tepest R (2007).
Disturbed frontal gyrification within families affected with schizophrenia.
J Psychiatr Res 41: 805-813
Georgi A, Abou Jamra R, Klein K, Villela AW, Schumacher J, Becker T, Paul T, Schmäl C, Höfels S, Klopp N, Illig T, Propping P, Cichon S,
Nöthen MM, Schulze TG*, Rietschel M (2007).
Possible association between genetic variants at the GRIN1 gene and schizophrenia with lifetime history of depressive symptoms in a German sample.
Psychiatr Genet 17: 308-310. *corresponding author
Goes FS, Sadler B, Toolan J, Zamoiski RD, Mondimore FM, Mackinnon DF, Schweizer B; Bipolar Disorder Phenome Group, Raymond Depaulo J Jr, Potash JB (2007).
Psychotic features in bipolar and unipolar depression.
Bipolar Disord 9: 901
Laucht M, Skowronek MH, Becker K, Schmidt MH, Esser G, Schulze TG, Rietschel M (2007).
Interacting effects of the dopamine transporter gene and psychosocial adversity on ADHD symptoms among 15-year-olds
from a high-risk community sample.
Arch Gen Psychiatry 64: 585-590
Potash JB, Toolan J, Steele J, Miller EB, Pearl J, Zandi PP, Schulze TG, Kassem L, Simpson SG, Lopez V; NIMH Genetics Initiative Bipolar Disorder
Consortium, MacKinnon DF, McMahon FJ (2007).
The bipolar disorder phenome database: a resource for genetic studies.
Am J Psychiatry 164: 1229-1237
Schirmbeck F, Georgi A, Strohmaier JM, Schmäl C, Knorr C, Abou Jamra R, Schumacher J, Becker T, Klopp N, Illig T, Wulf M, Schwarz M, Propping P,
Cichon S, Nöthen MM, Schulze TG, Rietschel M (2007).
No association between the serine racemase gene (SRR) and bipolar disorder in a German case-control sample.
Psychiatr Genet 17: 127
Schmael C, Georgi A, Krumm B, Buerger C, Deschner M, Nöthen MM, Schulze TG, Rietschel M (2007).
Premorbid adjustment in schizophrenia--an important aspect of phenotype definition.
Schizophr Res 92: 50-62
Strohmaier JM, Georgi A, Schirmbeck F, Schmäl C, Abou Jamra R, Schumacher J, Becker T, Höfels S, Klopp N, Illig T, Propping P, Cichon S,
Nöthen MM, Rietschel M, Schulze TG (2007).
No association between the serine racemase gene (SRR) and schizophrenia in a German case-control sample.
Psychiatr Genet 17: 125
2006 |
Abou Jamra R, Villela AW, Klein K, Becker T, Schulze TG, Schmael C, Deschner M, Klopp N, Illig T, Propping P, Cichon S,
Rietschel M, Nöthen MM, Schumacher J (2006).
No association between genetic variants at the GLYT2 gene and bipolar affective disorder and schizophrenia.
Psychiat Genet 16: 91
Calliess IT, Schulze TG, Treichel KC (2006).
The 5 year Young Psychiatrist Program: A contribution for the young generation in psychiatry in Germany.
Nervenarzt 77: 1407-1409
Etain B, Mathieu F, Rietschel M, Maier W, Albus M, McKeon P, Roche S, Kealey C, Blackwood D, Muir W, Bellivier F, Henry C, Dina C,
Gallina S, Gurling H, Malafosse A, Preisig M, Ferrero F, Cichon S, Schumacher J, Ohlraun S, Borrmann-Hassenbach M, Propping P,
Abou Jamra R, Schulze TG, Marusic A, Dernovsek ZM, Giros B, Bourgeron T, Bacq D, Lemainque A, Betard C, Charon C, Nöthen M,
Lathrop M, Leboyer M (2006).
Genome-wide scan for genes involved in bipolar affective disorder in 70 European families ascertained through a bipolar type I
early onset proband : supportive evidence for linkage at 3p14.
Mol Psychiatry 11: 685-694
Georgi A, Abou Jamra R, Schumacher J, Becker T, Schmael C, Deschner M, Höfels S, Wulff M, Schwarz M, Klopp N, Illig T, Propping P,
Cichon S, Nöthen MM, Rietschel M, Schulze TG (2006).
No association between genetic variants at the GRIN1 gene and bipolar disorder in a German sample.
Psychiat Genet 16: 183-184
Ivo R, Schulze TG, Schumacher J, Kesper K, Muller DJ, Kremer I, Dobrusin M, Mujaheed M, Murad I, Blanaru M, Bannoura I, Reshef A,
Bachner-Melman R, Ebstein RP, Propping P, Belmaker RH, Maier W, Rietschel M, Nothen MM, Cichon S (2006).
No evidence for association between NOTCH4 and schizophrenia in a large family-based and case-control association analysis.
Psychiatr Genet 16: 197-203
Jamra RA, Klein K, Villela AW, Becker T, Schulze TG, Schmael C, Deschner M, Klopp N, Illig T, Propping P, Cichon S,
Rietschel M, Nothen MM, Schumacher J (2006).
Association study between genetic variants at the PIP5K2A gene locus and schizophrenia and bipolar affective disorder.
Am J Med Genet B Neuropsychiatr Genet 141: 663-665
Jonsson EG, Cichon S, Schumacher J, Jamra RA, Schulze TG, Deschner M, Forslund K, Hall H, Propping P, Czerski PM,
Dmitrak-Weglarz M, Kapelski P, Driessen M, Maier W, Hauser J, Rietschel M, Nothen MM (2006).
Association study of a functional promoter polymorphism in the XBP1 gene and schizophrenia.
Am J Med Genet B Neuropsychiatr Genet 141: 71-75
Schneider-Axmann T, Kamer T, Moroni M, Maric N, Tepest R, Dani I, Honer WG, Scherk H, Rietschel M, Schulze TG, Muller DJ, Cordes J,
Schonell H, Steinmetz H, Gaebel W, Vogeley K, Kuhn KU, Wagner M, Maier W, Traber F, Block W, Schild HH, Falkai P (2006).
Relation between cerebrospinal fluid, gray matter and white matter changes in families with schizophrenia.
J Psychiatr Res 40: 646-655
Schulze TG, Hedeker D, Zandi P, Rietschel M, McMahon FJ (2006).
What is familial about familial bipolar disorder? Resemblance among relatives across a broad spectrum of phenotypic characteristics.
Arch Gen Psychiatry 63: 1368-1376
Skowronek MH, Georgi A, Abou Jamra R, Schumacher J, Becker T, Schmael C, Paul T, Deschner M, Hofels S, Wulff M, Schwarz M, Klopp N, Illig T,
Propping P, Cichon S, Nothen MM, Schulze TG, Rietschel M (2006).
No association between genetic variants at the ASCT1 gene and schizophrenia or bipolar disorder in a German sample.
Psychiatr Genet 16: 233-234
Xu W, Schulze TG, DePaulo JR, Bull SB, McMahon FJ (2006).
Greenwood CMT. A tree based model for allele-sharing-based linkage analysis in human complex diseases.
Genet Epidem 30: 155-169
2005 |
Abou Jamra R, Schumacher J, Becker T, Dahdouh F, Ohlraun S, Suliman H, Schulze TG, Tullius M, Kovalenko S, Maier W, Rietschel M,
Propping P, Nöthen MM, Cichon S (2005).
No evidence for an association between variants at the praline dehydrogenase locus and schizophrenia or bipolar affective disorder.
Psychiat Genet 15: 195-198
Abou Jamra R, Sirca I, Becker T, Freudenberg-Hua Y, Ohlraun S, Freudenberg J, Brockschmidt F, Schulze TG, Gross M, Spira F,
Deschner M, Schmäl C, Maier W, Propping P, Rietschel M, Cichon S, Nöthen MM, Schumacher J (2005).
A Family-Based and Case-Control Association Study of Trace Amine Receptor Genes on Chromosome 6q23 in Bipolar Affective Disorder.
Mol Psychiatry 10: 618-620
Fisfalen ME, Schulze TG, DePaulo JR, DeGroot LJ, Badner JA, McMahon FJ (2005).
Familial variation in episode frequency in bipolar affective disorder.
Am J Psychiatry 162: 1266-1272
Glaser B, Schumacher J, Williams H, Abou Jamra R, Ianakiev N, Milev R, Ohlraun S, Schulze TG, Czerski PM, Hauser J,
Jönsson EG, Sedvall GC, Klopp N, Illig T, Becker T, Propping P, Williams NM, Cichon S, Kirov G, Rietschel M, O Donovan MC,
Nöthen MM, Owen MJ (2005).
No association between ZDHHC8 and schizophrenia in large outbred and proband/parent panels of European origin.
Biol Psychiatry 58: 78-80
Hillmer AM, Hanneken S, Ritzmann, Becker T, Freudenberg J, Brockschmidt FF, Flaquer A, Freudenberg-Hua Y, Abou Jamra R, Metzen C,
Heyn U, Schweiger N, Betz RC, Hampe J, Schreiber S, Schulze TG, Hennies HC, Schumacher J, Propping P, Ruzicka T, Cichon S,
Wienker TF, Kruse R, Nöthen MM (2005).
Genetic variation in the human androgen receptor gene is the major determinant of common early onset androgenetic alopecia.
Am J Hum Genet 77: 140-18
Hoefgen B, Schulze TG*, Ohlraun S, Von Widdern O, Höfels S, Gross M, Heidmann V, Kovalenko S, Eckermann A, Kölsch A,
Metten M, Zobel A, Becker T, Nöthen MM, Propping P, Heun R, Maier W, Rietschel M (2005).
The power of sample size and homogenous sampling: association between the 5-HTTLPR serotonin transporter polymorphism and major depressive disorder.
Biol Psychiatry 57: 247-251. *corresponding author
McMahon FJ, Schulze TG (2005).
Bipolar disorder as a phenotype in genetic studies.
Clin Neuroscience Res 5: 37-43
Schulze TG, Ohlraun S, Czerski PM, Schumacher J, Kassem L, Deschner M, Gross M, Tullius M, Heidman V, Kovalenko S, Abou Jamra R,
Becker T, Leszczynska-Rodziewicz A, Hauser J, Illig T, Klopp N, Wellek S, Cichon S, Henn FA, McMahon FJ, Maier W, Propping P, Nöthen MM,
Rietschel M (2005).
Genotype-phenotype studies in bipolar disorder show association between the DAOA/G30 locus and persecutory delusions: A first step
towards a molecular genetic classification of psychiatric phenotypes.
Am J Psychiatry 162: 2101-2108
Schumacher J, Abou Jamra R, Becker T, Klopp N, Franke P, Jacob C, Sand P, Fritze J, Ohlraun S, Schulze TG, Rietschel M,
Illig T, Propping P, Cichon S, Deckert J, Nothen MM (2005).
Investigation of the DAOA/G30 locus in panic disorder.
Mol Psychiatry 10: 428-4299
Schumacher J, Abou Jamra R, Becker T, Ohlraun S, Klopp N, Binder E, Schulze TG, Deschner M, Braeman C, Höfels S, Maier W,
Illig T, Propping P, Holsboer F, Rietschel M, Nöthen MM, Cichon S (2005).
Evidence for a relationship between genetic variants at the brain-derived neurotrophic factor (BDNF) locus and major depression.
Biol Psychiatry 58: 307-314
Schumacher J, Kaneva R, Abou Jamra R,Diaz GO, Ohlraun S,Milanova V, Lee Y-A, Rivas F, Mazoral F, Fuerst F, Flaquer A, Windemuth C,
Gay E,Sans S, González MJ, Gil S, Cabaleiro F, del Rio F, Perez F, Haro J, Kostov C, Chorbov V, Nikolova-Hill A, Stoyanova V, Onchev G,
Kremensky I, Strauch K, Schulze TG, Nürnberg P, Gaebel W, Klimke A, Auburger G, Wienker TF, Kalaydjieva L, Propping P, Cichon S,
Jablensky A, Rietschel M, Nöthen MM (2005).
Genome-wide scan and fine mapping linkage studies in four European samples with bipolar affective disorder suggest a new susceptibility
locus on chromosome 1p35-p36 and provides further evidence for loci on chromosome 4q31 and 6q24.
Am J Hum Genet 77: 1102-1111
2004 |
Abou Jamra R, Schumacher J, Golla A, Richter C, Otte ACJ, Schulze TG, Ohlraun S, Maier W, Rietschel M, Cichon S, Propping P, Nöthen MM (2004).
Family-based association studies of alpha-adrenergic receptor genes in chromosomal regions with linkage to bipolar affective disorder.
Am J Med Genet 126B: 79-81
Chen Y-S, Akula N, Detera-Wadleigh SD, Schulze TG, Thomas J, Potash JB, DePaulo JR, McInis MG, Cox NJ, McMahon FJ (2004).
Findings in an independent sample support an association between bipolar affective disorder and the G72/G30 locus on chromosome 13q33.
Mol Psychiatry 9: 87-92
Cichon S, Buervenich S, Kirov G, Akula N, Dimitrova A, Green E, Schumacher J, Klopp N, Becker T, Ohlraun S, Schulze TG,
Tullius M, Gross MM, Jones L, Krastev S, Nikolov I, Hamshere M, Jones I, Czerski PM, Leszczynska-Rodziewicz A, Kapelski P, Bogaert AV,
Illig T, Hauser J, Maier W, Berrettini W, Byerley W, Coryell W, Gershon ES, Kelsoe JR, McInnis MG, Murphy DL, Nurnberger JI, Reich T,
Scheftner W, O'Donovan MC, Propping P, Owen MJ, Rietschel M, Nöthen MM, McMahon FJ, Craddock N (2004).
Lack of support for a genetic association of the XBP1 promoter polymorphism with bipolar disorder in probands of European origin.
Nat Genet 36: 783-784
Falkai P, Tepest R, Honer WG, Dani I, Ahle G, Pfeiffer U, Vogeley K, Schulze TG, Rietschel M, Cordes J, Schonell H, Gaebel W,
Kuhn KU, Maier W, Traber F, Block W, Schild HH, Schneider-Axmann T (2004).
Shape changes in prefrontal, but not parieto-occipital regions: brains of schizophrenic patients come closer to a circle in coronal and sagittal view.
Psychiatry Res 132: 261-71
Falkai P, Tepest R, Schulze TG, Müller DJ, Rietschel M, Maier W, Traber F, Block W, Schild HH, Steinmetz H, Gaebel W, Honer WG,
Schneider-Axmann T, Wagner M (2004).
Etiopathogenetic mechanisms in long-term course of schizophrenia.
Pharmacopsychiatry 37(Suppl 2): 136-140
Fangerau H, Ohlraun S, Granath RO, Nöthen MM, Rietschel M, Schulze TG (2004).
Computer-assisted phenotype characterization for genetic research in psychiatry.
Hum Heredity 58: 122-130
Gordon D, McMahon FJ, Schulze TG (Eds.).
Human Heredity, Vol.58/3-4: Issues in Association Analysis.
Basel 2004, Karger
Paus S, Rietschel M, Schulze TG, Ohlraun S, Diaconu CC, Den Bogaert AV, Maier W, Propping P, Cichon S, Nöthen MM (2004).
Systematic screening for mutations in the human N-methyl-D-aspartate receptor 1 gene in schizophrenic patients from the German population.
Psychiat Genet 14: 233-234
Prathikanti S, Schulze TG, Chen YS, Harr B, Akula N, Hennessy K, Potluri S, Lyons J, Nguyen T, McMahon FJ (2004).
Neither single-marker nor haplotype analyses support an association between genetic variation near NOTCH4 and bipolar disorder.
Am J Med Genet 131B: 10-15
Schulze TG, Buervenich S, Badner JA, Steele CJM, Detera-Wadleigh SD, Dick D, Foroud F, Cox NJ, MacKinnon DF, Potash JB,
Berrettini W, Byerley W, Coryell W, DePaulo JR, Gershon ES, Kelsoe JR, McInnis MG, Murphy DL, Reich T, Scheftner W,
Nurnberger JI, McMahon FJ (2004).
Loci on chromosomes 6q and 6p interact to increase susceptibility to bipolar affective disorder in the NIMH Genetics Initiative pedigrees.
Biol Psychiatry 56: 18-23
Schulze TG, Fangerau H, Propping P (2004).
From degeneration to genetic susceptibility, from eugenics to genethics, from Bezugsziffer to LOD score: the history of psychiatric genetics.
Int Rev Psychiatry 16: 246-59
Schulze TG, Zhang K, Chen Y-S, Akula N, Sun F, McMahon FJ (2004).
Defining haplotype blocks and tag single-nucleotide polymorphisms in the human genome.
Hum Mol Genet 13: 335-342
2003 |
Bellivier F, Golmard J-L, Rietschel M, Schulze TG, Malafosse A, Preisig M, McKeon P, Mynett-Johnson L, Henry C, Leboyer M (2003).
Age at onset in bipolar I affective disorder: further evidence for three subgroups.
Am J Psychiatry 160: 999-1001
Kremer I, Pinto M, Murad I, Muhaheed M, Bannoura I, Muller DJ, Schulze TG, Reshef A, Blanaru M, Gathas S, Goichman R, Rietschel M,
Dobrusin M, Bachner-Melman R, Nemanov L, Belmaker RH, Maier W, Ebstein RP (2003).
Family-based and case-control study of catechol-O-methyltransferase in schizophrenia among Palestinian Arabs.
Am J Med Genet 119B: 35-39
Lohmann PL, Bagli M, Krauss H, Muller DJ, Schulze TG, Fangerau H, Ludwig M, Barkow K, Held T, Heun R, Maier W, Rietschel M, Rao ML (2003).
CYP2D6 Polymorphism and Tardive Dyskinesia in Schizophrenic Patients.
Pharmacopsychiatry 36: 73-78
Schulze TG, Chen YS, Badner JA, McInnis MG, DePaulo JR, McMahon (2003).
Additional, physically-ordered markers increase evidence of linkage between bipolar disorder and chromosome 18q.
Biol Psychiatry 53: 239-243
Schulze TG, Cichon S, Propping P, Maier W, Nöthen M, Rietschel M (2003).
Is there a phenotypic difference between probands in case-control versus family-based association studies?
Am J Med Genet 118B: 25-6
Schulze TG, Hardy J, McMahon FJ (2003).
Inconsistent designs of association studies: a missed opportunity.
Mol Psychiatry 9: 770-772
Schulze TG, McMahon FJ (2003).
Genetic linkage and association studies in bipolar affective disorder: A time for optimism.
Am J Med Genet 123C: 36-47
Schwab SG, Mondabon S, Knapp M, Albus M, Hallmayer J, Borrmann-Hassenbach M, Trixler M, Gross M, Schulze TG, Lerer B, Maier W,
Wildenauer DB (2003).
Tumor necrosis factor alpha gene-G308A polymorphism: evidence for linkage disequilibrium with schizophrenia in 79 sib-pair-families
with linkage to the MHC region and in 128 trio-families with family history of psychiatric disorder.
Schizophrenia Res 65: 19-25
Van Den Bogaert A, Schumacher J, Schulze TG, Otte AC, Ohlraun S, Kovalenko S, Becker T, Freudenberg J, Jonsson EG,
Mattila-Evenden M, Sedvall GC, Czerski PM, Kapelski P, Hauser J, Maier W, Rietschel M, Propping P, Nothen MM, Cichon S (2003).
The DTNBP1 (Dysbindin) gene contributes to schizophrenia, depending on family history of the disease.
Am J Hum Genet 73: 1438-1443
2002 |
Akula N, Chen YS, Hennessy K, Schulze TG, Singh G, McMahon FJ (2002).
Utility and accuracy of template-directed dye-terminator incorporation with fluorescence-polarization detection (FP-TDI)
for genotyping single nucleotide polymorphims.
Biotechniques 32: 1072-1078
Jahnes E, Müller DJ, Schulze TG, Windemuth C, Cichon S, Ohlraun S, Fangerau H, Held T, Maier W, Propping P, Nöthen MM, Rietschel M (2002).
Association study between two variants in the DOPA decarboxylase gene in bipolar and unipolar affective disorder.
Am J Med Genet 114: 523-526
Müller DJ, Schulze TG, Jahnes E, Cichon S, Krauss H, Kesper K, Held T, Maier W, Propping P, Nöthen MM, Rietschel M (2002).
Association between a polymorphism in the pseudoautosomal X-linked gene SYBL1 and bipolar affective disorder.
Am J Med Genet 114: 74-78
Müller DJ, Schulze TG, Macciardi F, Ohlraun S, Gross MM, Scherk H, Neidt H, Syagailo YV, Grassle M, Nöthen MM, Maier W, Lesch KP,
Rietschel M (2002).
Moclobemide response in depressed patients: association study with a functional polymorphism in the monoamine oxidase A promoter.
Pharmacopsychiatry 35: 157-158
Schulze TG, Chen YS, Akula YS, Hennessy K, Badner JA, McInnis MG, DePaulo JR, Schumacher J, Cichon S, Propping P, Maier W,
Rietschel M, Nöthen MM, McMahon FJ (2002).
Can long-range microsatellite data be used to predict short-range linkage disequilibrium?
Hum Mol Genet 11: 1363-1372
Schulze TG, McMahon FJ (2002).
Genetic association mapping at the crossroads: which test and why? Overview and practical guidelines.
Am J Med Genet 114: 1-11
Schulze TG, Müller DJ, Krauss H, Gross M, Fangerau-Lefèvre H, Illés F, Ohlraun S, Cichon S, Held T, Propping P, Nöthen MM,
Maier W, Rietschel M (2002).
Further evidence for age of onset being an indicator for severity in bipolar disorder.
J Affect Disord 68: 343-345
Schulze TG, Treichel KC (2002).
The European Federation of Psychiatric Trainees (EFPT) An integral part of the European harmonisation of psychiatric education and practise.
Eur Psychiatry 17: 300-305
2001 |
Cichon S, Schmidt-Wolf G, Schumacher J, Müller DJ, Hürter M, Schulze TG, Albus M, Borrmann-Hassenbach M, Franzek E, Lanczik M,
Fritze J, Kreiner R, Weigelt B, Minges J, Lichtermann D, Lerer B, Kanyas K, Strauch K, Windemuth C, Baur MP, Wienker TF, Maier W,
Rietschel M, Propping P, Nöthen MM (2001).
A susceptibility locus for bipolar affective disorder in chromosomal region 10q25-q26.
Mol Psychiatry 6: 342-349
Cichon S, Schumacher J, Müller DJ, Hürter M, Windemuth C, Strauch K, Hemmer S, Schulze TG, Schmidt-Wolf G, Albus M,
Borrmann-Hassenbach M, Franzek E, Lanczik M, Fritze J, Kreiner R, Reuner U, Weigelt B, Minges J, Lichtermann D, Lerer B, Kanyas K,
Baur MP, Wienker TF, Maier W, Rietschel M, Propping P, Nöthen MM (2001).
A genome screen for genes predisposing to bipolar affective disorder detects a new susceptibility locus on 8q and suggests
evidence for an involvement of imprinted loci.
Hum Mol Genet 10: 2933-2944
Dobrusin M, Corbex M, Kremer I, Murad I, Muhaheed M, Bannoura I, Müller DJ, Schulze TG, Reshef A, Blanaru M, Gathas S,
Rietschel M, Belmaker RH, Maier W, Ebstein RP (2001).
No evidence for linkage by transmission disequilibrium test analysis of microsatellite marker D22S278 and schizophrenia
in a Palestinian Arab and in a German Population.
Am J Med Genet 105: 328-331
Müller DJ, Schulze TG, Knapp M, Krauss H, Weber T, Ahle G, Maroldt A, Alfter D, Held T, Maier W, Nöthen MM, Rietschel M (2001).
Familial occurrence of tardive dyskinesia.
Acta Psychiatr Scand 104: 375-379
Murad I, Kremer I, Dobrusin M, Muhaheed M, Bannoura I, Müller DJ, Schulze TG, Reshef A, Blanaru M, Gathas S, Tsenter V,
Rietschel M, Belmaker RH, Maier W, Ebstein RP (2001).
A family-based study of the Cys23Ser 5HT2C-serotonin receptor polymorphism in schizophrenia.
Am J Med Genet 105: 236-238
Schulze TG, Müller DJ, Krauss H, Gross M, Bauer I, Fangerau-Lefèvre H, Illés F, Ohlraun S, Fimmers R, Cichon S, Held T,
Propping P, Nöthen MM, Maier W, Rietschel M (2001).
Caught in the "trio-trap"? - Potential selection bias inherent to association studies using parent-offspring trios.
Am J Med Genet 105: 351-353
Schulze TG, Müller DJ, Krauss H, Marwinski K, Novo y Fernández A, Maroldt A-O, Fimmers R, Held T, Maier W, Nöthen MM, Rietschel M (2001).
Affective symptomatology in schizophrenia: a risk factor for tardive dyskinesia?
Eur Psychiatry 16: 71-74
Schulze TG, Schumacher J, Müller DJ, Krauss H, Alfter D, Maroldt A, Ahle G, Maroldt A-O, Novo y Fernández A, Weber T,
Held T, Propping P, MaierW, Nöthen MM, Rietschel M (2001).
Lack of association between a functional polymorphism of the cytochrome P450 1A2 (CYP1A2) gene and tardive dyskinesia in schizophrenia.
Am J Med Genet 105: 498-501
Serretti A, Rietschel M, Lattuada E, Krauss H, Schulze TG, Müller DJ, Maier W, Smeraldi E (2001).
Major Psychoses Symptomatology: Factor Analysis of 2241 Psychotic Subjects.
Eur Arch Psychiatry Clin Neurosci 251: 193-198
Souery D, Van Gestel S, Massat I, Blairy S, Adolfsson R, Blackwood D, Del-Favero J, Dikeos D, Jakovljevic M, Kaneva R, Lattuada E,
Lerer B, Lilli R, Milanova V, Muir W, Nöthen M, Oruc L, Papadimitriou G, Propping P, Schulze T, Serretti A, Shapira B,
Smeraldi E, Stefanis C, Thomson M, van Broeckhoven C, Mendlewicz J (2001).
Tryptophane hydroxylase polymorphism and suicidality in unipolar and bipolar affective disorders: a multicenter association study.
Biol Psychiatry 49: 405-409
2000 |
Block W, Bayer TA, Träber F, Tepest R, Stabenow M, Rietschel M, Müller DJ, Schulze TG, Rolf Lamerichs R, Honer WG, Held T,
Maier W, Schild HH, Falkai P (2000).
Decreased frontal lobe ratio of N-acetyl aspartate to choline in familial schizophrenia: a proton magnetic resonance spectroscopy study.
Neurosci Lett 289: 147-151
Grünhage F, Schulze TG, Müller DJ, Lanczik M, Franzek E, Albus M, Borrmann-Hassenbach M, Knapp M, Cichon S, Maier W,
Rietschel M, Propping P, Nöthen MM (2000).
Systematic screening for DNA sequence variation in the coding region of the human dopamin transporter gene (DAT1).
Mol Psychiatry 5: 275-282
Held T, Weber T, Krauss H, Ahle G, Hager B, Alfter D, Schulze T, Knapp M, Maier W, Rietschel M (2000).
Clinical characteristics of patients with tardive dyskinesia.
Fortschr Neurol Psychiatr 68: 321-331
Krauss H, Marwinski K, Schulze T, Müller DJ, Rietschel M, Held T, Maier W, Freyberger HJ (2000).
Data on the reliability and validity of the German Version of the Premorbid Adjustment Scale.
Nervenarzt 71: 188-194
Kremer I, Rietschel M, Dobrusin M, Mujaheed M, Murad I, Blanaru M, Bannoura A, Müller DJ, Schulze TG, Reshef A, Gathas S, Schwab S,
Wildenauer D, Bachner-Melman R, Belmaker RH, Maier W, Ebstein RP (2000).
No association between the dopamine D3 receptor Bal I polymorphism and schizophrenia in a family based study of Palestinian Arab population.
Am J Med Genet 96: 778-780
Rietschel M, Krauss H, Müller DJ, Schulze TG, Knapp M, Marwinski K, Maroldt AO, Paus S, Grünhage F, Propping P,
Maier W, Held T, Nöthen MM (2000).
Dopamine D3 receptor variant and tardive dyskinesia.
Eur Arch Psychiatry Clin Neurosci 250: 31-35
Rietschel M, Schorr A, Albus M, Franzek E, Kreiner R, Held T, Knapp M, Müller DJ, Schulze TG, Propping P, Maier W, Nöthen MM (2000).
Association study of the tryptophan hydroxylase gene and bipolar affective disorder using family-based internal controls.
Am J Med Genet 96: 310-311
Schulze TG, Müller DJ, Krauss H, Scherk H, Ohlraun S, Syagailo YV, Windemuth C, Neidt H, Grässle M, Papassotiropoulos A,
Heun R, Nöthen MM, Maier W, Lesch KP, Rietschel M (2000).
Association between a functional polymorphism in the monoamine oxidase A gene promoter and major depressive disorder.
Am J Med Genet 96: 801-803
Schumacher J, Schulze TG, Wienker TF, Rietschel M, Nöthen MM (2000).
Pharmacogenetics of clozapine response.
Lancet 356: 506-507
Vogt IR, Shimron-Abarbanell D, Neidt H, Erdmann J, Rietschel M, Schulze TG, Müller DJ, Maier W, Albus M, Borrmann-Hassenbach M,
Knapp M, Propping P, Nöthen MM (2000).
Investigation of the human serotonin 6 (5-HT6) receptor gene in bipolar affective disorder and schizophrenia.
Am J Med Genet 96: 217-221
1998 |
Krauss H, Knapp M, Schulze T, Rietschel M (1998).
Premorbid adjustment and schizophrenia.
Br J Psychiatry 173: 36
1994 |
Pfeiffer RA, Schulze T (1994).
Mosaicism in three cases of 47, XY (or XX), +i(18)(p10) detected by interphase FISH of buccal mucosa.
Ann Genet 37: 210-14
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